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TNFα enhances force generation in airway smooth muscle

Airway inflammation is a hallmark of asthma, triggering airway smooth muscle (ASM) hyperreactivity and airway remodeling. TNFα increases both agonist-induced cytosolic Ca(2+) concentration ([Ca(2+)](cyt)) and force in ASM. The effects of TNFα on ASM force may also be due to an increase in Ca(2+) sen...

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Bibliografiska uppgifter
I publikationen:Am J Physiol Lung Cell Mol Physiol
Huvudupphovsmän: Dogan, Murat, Han, Young-Soo, Delmotte, Philippe, Sieck, Gary C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495949/
https://ncbi.nlm.nih.gov/pubmed/28385814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00550.2016
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