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TNFα enhances force generation in airway smooth muscle
Airway inflammation is a hallmark of asthma, triggering airway smooth muscle (ASM) hyperreactivity and airway remodeling. TNFα increases both agonist-induced cytosolic Ca(2+) concentration ([Ca(2+)](cyt)) and force in ASM. The effects of TNFα on ASM force may also be due to an increase in Ca(2+) sen...
Enregistré dans:
| Publié dans: | Am J Physiol Lung Cell Mol Physiol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5495949/ https://ncbi.nlm.nih.gov/pubmed/28385814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00550.2016 |
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