The CFTR trafficking mutation F508del inhibits the constitutive activity of SLC26A9

Several members of the SLC26A family of anion transporters associate with CFTR, forming complexes in which CFTR and SLC26A functions are reciprocally regulated. These associations are thought to be facilitated by PDZ scaffolding interactions. CFTR has been shown to be positively regulated by NHERF-1...

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Publicat a:Am J Physiol Lung Cell Mol Physiol
Autors principals: Bertrand, Carol A., Mitra, Shalini, Mishra, Sanjay K., Wang, Xiaohui, Zhao, Yu, Pilewski, Joseph M., Madden, Dean R., Frizzell, Raymond A.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2017
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495941/
https://ncbi.nlm.nih.gov/pubmed/28360110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00178.2016
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