The CFTR trafficking mutation F508del inhibits the constitutive activity of SLC26A9

Several members of the SLC26A family of anion transporters associate with CFTR, forming complexes in which CFTR and SLC26A functions are reciprocally regulated. These associations are thought to be facilitated by PDZ scaffolding interactions. CFTR has been shown to be positively regulated by NHERF-1...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Bertrand, Carol A., Mitra, Shalini, Mishra, Sanjay K., Wang, Xiaohui, Zhao, Yu, Pilewski, Joseph M., Madden, Dean R., Frizzell, Raymond A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495941/
https://ncbi.nlm.nih.gov/pubmed/28360110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00178.2016
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