A comprehensive analysis of myocardial substrate preference emphasizes the need for a synchronized fluxomic/metabolomic research design

The heart oxidizes fatty acids, carbohydrates, and ketone bodies inside the tricarboxylic acid (TCA) cycle to generate the reducing equivalents needed for ATP production. Competition between these substrates makes it difficult to estimate the extent of pyruvate oxidation. Previously, hyperpolarized...

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Bibliografische gegevens
Gepubliceerd in:Am J Physiol Heart Circ Physiol
Hoofdauteurs: Ragavan, Mukundan, Kirpich, Alexander, Fu, Xiaorong, Burgess, Shawn C., McIntyre, Lauren M., Merritt, Matthew E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2017
Onderwerpen:
Innovative Methodology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495932/
https://ncbi.nlm.nih.gov/pubmed/28411229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00016.2017
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