A comprehensive analysis of myocardial substrate preference emphasizes the need for a synchronized fluxomic/metabolomic research design

The heart oxidizes fatty acids, carbohydrates, and ketone bodies inside the tricarboxylic acid (TCA) cycle to generate the reducing equivalents needed for ATP production. Competition between these substrates makes it difficult to estimate the extent of pyruvate oxidation. Previously, hyperpolarized...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Ragavan, Mukundan, Kirpich, Alexander, Fu, Xiaorong, Burgess, Shawn C., McIntyre, Lauren M., Merritt, Matthew E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Innovative Methodology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495932/
https://ncbi.nlm.nih.gov/pubmed/28411229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00016.2017
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