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The impact of the butterfly effect on human parainfluenza virus haemagglutinin-neuraminidase inhibitor design

Human parainfluenza viruses represent a leading cause of lower respiratory tract disease in children, with currently no available approved drug or vaccine. The viral surface glycoprotein haemagglutinin-neuraminidase (HN) represents an ideal antiviral target. Herein, we describe the first structure-b...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Dirr, Larissa, El-Deeb, Ibrahim M., Chavas, Leonard M. G., Guillon, Patrice, Itzstein, Mark von
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495814/
https://ncbi.nlm.nih.gov/pubmed/28674426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04656-y
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