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Analysis of inhibitor binding in influenza virus neuraminidase

2,3-didehydro-2-deoxy-N-acetylneuraminic acid (DANA) is a transition state analog inhibitor of influenza virus neuraminidase (NA). Replacement of the hydroxyl at the C(9) position in DANA and 4-amino-DANA with an amine group, with the intention of taking advantage of an increased electrostatic inter...

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Bibliografiske detaljer
Main Authors: Smith, Brian J., Colman, Peter M., Von Itzstein, Mark, Danylec, Basil, Varghese, Joseph N.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373964/
https://ncbi.nlm.nih.gov/pubmed/11274459
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