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PAX2 is dispensable for in vitro nephron formation from human induced pluripotent stem cells

The kidney is formed by reciprocal interactions between the nephron progenitor and the ureteric bud, the former of which gives rise to the epithelia of nephrons consisting of glomeruli and renal tubules. The transcription factor PAX2 is essential for this mesenchymal-to-epithelial transition of neph...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kaku, Yusuke, Taguchi, Atsuhiro, Tanigawa, Shunsuke, Haque, Fahim, Sakuma, Tetsushi, Yamamoto, Takashi, Nishinakamura, Ryuichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495778/
https://ncbi.nlm.nih.gov/pubmed/28674456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04813-3
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