MBOAT7 rs641738 variant and hepatocellular carcinoma in non-cirrhotic individuals

Nonalcoholic fatty liver disease (NAFLD) represents an emerging cause of hepatocellular carcinoma (HCC), especially in non-cirrhotic individuals. The rs641738 C > T MBOAT7/TMC4 variant predisposes to progressive NAFLD, but the impact on hepatic carcinogenesis is unknown. In Italian NAFLD patients...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Donati, Benedetta, Dongiovanni, Paola, Romeo, Stefano, Meroni, Marica, McCain, Misti, Miele, Luca, Petta, Salvatore, Maier, Silvia, Rosso, Chiara, De Luca, Laura, Vanni, Ester, Grimaudo, Stefania, Romagnoli, Renato, Colli, Fabio, Ferri, Flaminia, Mancina, Rosellina Margherita, Iruzubieta, Paula, Craxi, Antonio, Fracanzani, Anna Ludovica, Grieco, Antonio, Corradini, Stefano Ginanni, Aghemo, Alessio, Colombo, Massimo, Soardo, Giorgio, Bugianesi, Elisabetta, Reeves, Helen, Anstee, Quentin M., Fargion, Silvia, Valenti, Luca
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495751/
https://ncbi.nlm.nih.gov/pubmed/28674415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04991-0
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