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Molecular interaction between type 2 diabetes and Alzheimer’s disease through cross-seeding of protein misfolding

Numerous epidemiological studies have shown a significantly higher risk for development of Alzheimer’s disease (AD) in patients affected by type 2 diabetes (T2D), but the molecular mechanism responsible for this association is presently unknown. Both diseases are considered protein misfolding disord...

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Vydáno v:Mol Psychiatry
Hlavní autoři: Moreno-Gonzalez, Ines, Edwards, George, Salvadores, Natalia, Shahnawaz, Mohammad, Diaz-Espinoza, Rodrigo, Soto, Claudio
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495631/
https://ncbi.nlm.nih.gov/pubmed/28044060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2016.230
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