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Splicing stimulates siRNA formation at Drosophila DNA double-strand breaks
DNA double-strand breaks trigger the production of locus-derived siRNAs in fruit flies, human cells and plants. At least in flies, their biogenesis depends on active transcription running towards the break. Since siRNAs derive from a double-stranded RNA precursor, a major question is how broken DNA...
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| Publicado no: | PLoS Genet |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5495518/ https://ncbi.nlm.nih.gov/pubmed/28628606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006861 |
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