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Endo-siRNAs depend on a new isoform of loquacious and target artificially introduced, high-copy sequences

Colonization of genomes by a new selfish genetic element is detrimental to the host species and must lead to an efficient, repressive response. In vertebrates as well as in Drosophila, piRNAs repress transposons in the germ line, whereas endogenous siRNAs take on this role in somatic cells. We show...

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Detalhes bibliográficos
Main Authors: Hartig, Julia Verena, Esslinger, Stephanie, Böttcher, Romy, Saito, Kuniaki, Förstemann, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760103/
https://ncbi.nlm.nih.gov/pubmed/19644447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.220
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