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Endo-siRNAs depend on a new isoform of loquacious and target artificially introduced, high-copy sequences

Colonization of genomes by a new selfish genetic element is detrimental to the host species and must lead to an efficient, repressive response. In vertebrates as well as in Drosophila, piRNAs repress transposons in the germ line, whereas endogenous siRNAs take on this role in somatic cells. We show...

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Détails bibliographiques
Auteurs principaux: Hartig, Julia Verena, Esslinger, Stephanie, Böttcher, Romy, Saito, Kuniaki, Förstemann, Klaus
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760103/
https://ncbi.nlm.nih.gov/pubmed/19644447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.220
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