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Processing of Drosophila endo-siRNAs depends on a specific Loquacious isoform

Drosophila melanogaster expresses three classes of small RNAs, which are classified according to their mechanisms of biogenesis. MicroRNAs are ∼22–23 nucleotides (nt), ubiquitously expressed small RNAs that are sequentially processed from hairpin-like precursors by Drosha/Pasha and Dcr-1/Loquacious...

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Hlavní autoři: Zhou, Rui, Czech, Benjamin, Brennecke, Julius, Sachidanandam, Ravi, Wohlschlegel, James A., Perrimon, Norbert, Hannon, Gregory J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743050/
https://ncbi.nlm.nih.gov/pubmed/19635780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1611309
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