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Structural and dynamical insight into thermally induced functional inactivation of firefly luciferase

Luciferase is the key component of light production in bioluminescence process. Extensive and advantageous application of this enzyme in biotechnology is restricted due to its low thermal stability. Here we report the effect of heating up above T(m) on the structure and dynamical properties of lucif...

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Veröffentlicht in:PLoS One
Hauptverfasser: Jazayeri, Fatemeh S., Amininasab, Mehriar, Hosseinkhani, Saman
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495494/
https://ncbi.nlm.nih.gov/pubmed/28672033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180667
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