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Illuminating insights into firefly luciferase and other bioluminescent reporters used in chemical biology

Understanding luciferase enzymology and the structure of compounds that modulate luciferase activity can be used to improve the design of luminescence-based assays. This review provides an overview of these popular reporters with an emphasis on the commonly used firefly luciferase from Photinus pyra...

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Hlavní autoři: Thorne, Natasha, Inglese, James, Auld, Douglas S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925662/
https://ncbi.nlm.nih.gov/pubmed/20609414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2010.05.012
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