Cardioprotective effects of PKG activation by soluble GC activator, BAY 60-2770, in ischemia-reperfusion-injured rat hearts

Soluble guanylate cyclase (sGC) has been suggested as a therapeutic target for cardiac ischemia-reperfusion (IR) injury. Until now, the molecular mechanism of BAY 60–2770, a sGC activator, in cardiac IR injury has not been assessed. To identify the cardioprotective effects of BAY 60–2770 in IR-injur...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lee, Kyung Hye, Lee, So-Ra, Cho, Haneul, Woo, Jong Shin, Kang, Jung Hee, Jeong, Yun-Mi, Cheng, Xian Wu, Kim, Woo-Shik, Kim, Weon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495340/
https://ncbi.nlm.nih.gov/pubmed/28671970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180207
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