The sGC activator BAY 60-2770 has potent erectile activity in the rat

Nitric oxide (NO) is the principal mediator of penile erection, and soluble guanylate cyclase (sGC) is the receptor for NO. In pathophysiological conditions when sGC is inactivated and not responsive to NO or sGC stimulators a new class of agents called sGC activators increase the activity of NO-ins...

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Hlavní autoři: Lasker, George F., Pankey, Edward A., Frink, Terrence J., Zeitzer, Jonathan R., Walter, Korey A., Kadowitz, Philip J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2013
Témata:
Cardiovascular Neurohormonal Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680766/
https://ncbi.nlm.nih.gov/pubmed/23585129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00062.2013
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