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Human genome-wide repair map of DNA damage caused by the cigarette smoke carcinogen benzo[a]pyrene
Benzo[a]pyrene (BaP), a polycyclic aromatic hydrocarbon, is the major cause of lung cancer. BaP forms covalent DNA adducts after metabolic activation and induces mutations. We have developed a method for capturing oligonucleotides carrying bulky base adducts, including UV-induced cyclobutane pyrimid...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5495276/ https://ncbi.nlm.nih.gov/pubmed/28607059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1706021114 |
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