Maintenance of antiangiogenic and antitumor effects by orally active low-dose capecitabine for long-term cancer therapy

Long-term uninterrupted therapy is essential for maximizing clinical benefits of antiangiogenic drugs (AADs) in cancer patients. Unfortunately, nearly all clinically available AADs are delivered to cancer patients using disrupted regimens. We aim to develop lifetime, nontoxic, effective, orally acti...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Zhang, Yin, Sun, Meili, Huang, Guichun, Yin, Linlin, Lai, Qinghua, Yang, Yunlong, Xing, Xiaoming, Yu, Guohua, Sun, Yuping, Wang, Xinsheng, Nie, Guohui, Liu, Yizhi, Cao, Yihai
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2017
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PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495268/
https://ncbi.nlm.nih.gov/pubmed/28607065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705066114
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