Lumacaftor/ivacaftor combination for CF patients homozygous for Phe508del-CFTR

Cystic Fibrosis (CF) is a life-shortening inherited disease caused by the loss or dysfunction of the CF transmembrane conductance regulator (CFTR) channel activity resulting from mutations in the CFTR gene. Phe508del is the most prevalent mutation with approximately 90% of CF patients carries it on...

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Bibliografiska uppgifter
I publikationen:Drugs Today (Barc)
Huvudupphovsmän: Zhang, Weiqiang, Zhang, Xiaoying, Zhang, Yanhui H., Stokes, Dennis C, Naren, Anjaparavanda P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495103/
https://ncbi.nlm.nih.gov/pubmed/27252987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1358/dot.2016.52.4.2467205
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