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Lumacaftor/ivacaftor combination for CF patients homozygous for Phe508del-CFTR

Cystic Fibrosis (CF) is a life-shortening inherited disease caused by the loss or dysfunction of the CF transmembrane conductance regulator (CFTR) channel activity resulting from mutations in the CFTR gene. Phe508del is the most prevalent mutation with approximately 90% of CF patients carries it on...

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Podrobná bibliografie
Vydáno v:Drugs Today (Barc)
Hlavní autoři: Zhang, Weiqiang, Zhang, Xiaoying, Zhang, Yanhui H., Stokes, Dennis C, Naren, Anjaparavanda P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495103/
https://ncbi.nlm.nih.gov/pubmed/27252987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1358/dot.2016.52.4.2467205
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