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Lumacaftor/ivacaftor combination for CF patients homozygous for Phe508del-CFTR
Cystic Fibrosis (CF) is a life-shortening inherited disease caused by the loss or dysfunction of the CF transmembrane conductance regulator (CFTR) channel activity resulting from mutations in the CFTR gene. Phe508del is the most prevalent mutation with approximately 90% of CF patients carries it on...
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| Udgivet i: | Drugs Today (Barc) |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5495103/ https://ncbi.nlm.nih.gov/pubmed/27252987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1358/dot.2016.52.4.2467205 |
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