Selective blockade of inhibitory Fcγ receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cells

The final differentiation or maturation of dendritic cells (DCs) in response to environmental stimuli influences their ability to both initiate immunity and determine the quality of the response to antigens. Circulating immune complexes and cell-bound immunoglobulins present in normal human sera rep...

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Main Authors: Dhodapkar, Kavita M., Kaufman, Jacob L., Ehlers, Marc, Banerjee, Devi K., Bonvini, Ezio, Koenig, Scott, Steinman, Ralph M., Ravetch, Jeffrey V., Dhodapkar, Madhav V.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC549508/
https://ncbi.nlm.nih.gov/pubmed/15703291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500014102
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