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Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers

RNA editing, a widespread post-transcriptional mechanism, has emerged as a new player in cancer biology. Recent studies have reported key roles for individual miRNA editing events, but a comprehensive picture of miRNA editing in human cancers remains largely unexplored. Here, we systematically chara...

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Vydáno v:Genome Res
Hlavní autoři: Wang, Yumeng, Xu, Xiaoyan, Yu, Shuangxing, Jeong, Kang Jin, Zhou, Zhicheng, Han, Leng, Tsang, Yiu Huen, Li, Jun, Chen, Hu, Mangala, Lingegowda S., Yuan, Yuan, Eterovic, A. Karina, Lu, Yiling, Sood, Anil K., Scott, Kenneth L., Mills, Gordon B., Liang, Han
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495064/
https://ncbi.nlm.nih.gov/pubmed/28411194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.219741.116
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