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Mechanisms of precise genome editing using oligonucleotide donors
The use of programmable meganucleases is transforming genome editing and functional genomics. CRISPR/Cas9 was developed such that targeted genomic lesions could be introduced in vivo with unprecedented ease. In the presence of homology donors, these lesions facilitate high-efficiency precise genome...
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| Publicado no: | Genome Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5495063/ https://ncbi.nlm.nih.gov/pubmed/28356322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.214775.116 |
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