DHFR and MDR1 upregulation is associated with chemoresistance in osteosarcoma stem-like cells

Tumor-initiating cells (TICs) are defined as a specialized subset of cells with tumor-initiating capacity that can initiate tumor growth, tumor relapse and metastasis. In the present study, osteosarcoma TICs (OS-TICs) were isolated and enriched from the osteosarcoma U2OS and MG-63 cell lines using s...

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Pubblicato in:Oncol Lett
Autori principali: Lee, Yu-Hsien, Yang, Hui-Wen, Yang, Li-Chiu, Lu, Ming-Yi, Tsai, Lo-Lin, Yang, Shun-Fa, Huang, Yu-Feng, Chou, Ming-Yung, Yu, Cheng-Chia, Hu, Fang-Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2017
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494897/
https://ncbi.nlm.nih.gov/pubmed/28693150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6132
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