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Role of the intestinal tight junction modulator zonulin in the pathogenesis of type I diabetes in BB diabetic-prone rats

Increased intestinal permeability has been observed in numerous human autoimmune diseases, including type-1 diabetes (T1D) and its' animal model, the BB-wor diabetic prone rat. We have recently described zonulin, a protein that regulates intercellular tight junctions. The objective of this stud...

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Detalhes bibliográficos
Main Authors: Watts, Tammara, Berti, Irene, Sapone, Anna, Gerarduzzi, Tania, Not, Tarcisio, Zielke, Ronald, Fasano, Alessio
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC549484/
https://ncbi.nlm.nih.gov/pubmed/15710870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500178102
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