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Elevated levels of mRNAs encoding dihydropyrimidine dehydrogenase and thymidylate synthase are associated with improved survival of patients with hepatocellular carcinoma treated with S-1

Thymidylate synthase (TYMS) and dihydropyrimidine dehydrogenase (DPYD) are associated with the response of tumors to fluoropyrimidines. The aim of the present study was to investigate the association between the levels of TYMS and DPYD mRNAs and the efficacy of S-1 for treating patients with HCC. A...

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Publicado en:Oncol Lett
Main Authors: Okano, Yusuke, Kuramochi, Hidekazu, Nakajima, Go, Katagiri, Satoshi, Yamamoto, Masakazu
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494709/
https://ncbi.nlm.nih.gov/pubmed/28693254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6241
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