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RKTG overexpression inhibits proliferation and induces apoptosis of human leukemia cells via suppression of the ERK and PI3K/AKT signaling pathways

Raf kinase trapping to Golgi (RKTG) is reported to be a tumor suppressor in a number of solid tumors due to its negative modulation of the Ras/Raf/mitogen-activated protein kinase kinase/extracellular signal-regulated kinase (ERK) pathways. However, the role of RKTG in the progression of leukemia re...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Xu, Yingdong, Deng, Na, Wang, Xiaoou, Chen, Yinghui, Li, Guiji, Fan, Hua
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494687/
https://ncbi.nlm.nih.gov/pubmed/28693259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6182
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