Pirfenidone may revert the epithelial-to-mesenchymal transition in human lung adenocarcinoma

The epithelial-to-mesenchymal transition (EMT) in cancer is associated with invasion, metastasis and chemoresistance. Recent studies have revealed the increased expression of programmed death-ligand 1 (PD-L1) in cells undergoing EMT. The underlying mechanism of EMT involves transforming growth facto...

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Détails bibliographiques
Publié dans:Oncol Lett
Auteurs principaux: Kurimoto, Ryota, Ebata, Takahiro, Iwasawa, Shunichiro, Ishiwata, Tsukasa, Tada, Yuji, Tatsumi, Koichiro, Takiguchi, Yuichi
Format: Artigo
Langue:Inglês
Publié: D.A. Spandidos 2017
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494670/
https://ncbi.nlm.nih.gov/pubmed/28693256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6188
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