Drug resistance originating from a TGF-β/FGF-2-driven epithelial-to-mesenchymal transition and its reversion in human lung adenocarcinoma cell lines harboring an EGFR mutation

Epithelial-to-mesenchymal transition (EMT) is a malignant cancer phenotype characterized by augmented invasion and metastasis, chemoresistance, and escape from host-immunity. This study sought to identify efficient methods for inducing EMT reversion, to evaluate alterations in chemosensitivity and i...

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Detalhes bibliográficos
Publicado no:Int J Oncol
Main Authors: KURIMOTO, RYOTA, IWASAWA, SHUNICHIRO, EBATA, TAKAHIRO, ISHIWATA, TSUKASA, SEKINE, IKUO, TADA, YUJI, TATSUMI, KOICHIRO, KOIDE, SHUHEI, IWAMA, ATSUSHI, TAKIGUCHI, YUICHI
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4809654/
https://ncbi.nlm.nih.gov/pubmed/26984042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2016.3419
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