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Interruption of ganglioside synthesis produces central nervous system degeneration and altered axon–glial interactions
Gangliosides, which are sialylated glycosphingolipids, are the major class of glycoconjugates on neurons and carry the majority of the sialic acid within the central nervous system (CNS). To determine the role of ganglioside synthesis within the CNS, mice carrying null mutations in two critical gang...
Enregistré dans:
| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC549464/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15710896/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0407785102 |
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