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Systemic inflammation in glucocerebrosidase-deficient mice with minimal glucosylceramide storage
Gaucher disease, the most common lysosomal storage disease, is caused by a deficiency of glucocerebrosidase resulting in the impairment of glucosylceramide degradation. The hallmark of the disease is the presence of the Gaucher cell, a macrophage containing much of the stored glucosylceramide found...
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| Главные авторы: | , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150961/ https://ncbi.nlm.nih.gov/pubmed/11994410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14530 |
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