Control of antiviral defenses through hepatitis C virus disruption of retinoic acid-inducible gene-I signaling

Hepatitis C virus (HCV) is a major human pathogen that infects 170 million people. A hallmark of HCV is its ability to establish persistent infections reflecting the evasion of host immunity and interference with α/β-IFN innate immune defenses. We demonstrate that disruption of retinoic acid-inducib...

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Main Authors: Foy, Eileen, Li, Kui, Sumpter, Rhea, Loo, Yueh-Ming, Johnson, Cynthia L., Wang, Chunfu, Fish, Penny Mar, Yoneyama, Mitsutoshi, Fujita, Takashi, Lemon, Stanley M., Gale, Michael
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC549461/
https://ncbi.nlm.nih.gov/pubmed/15710892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408707102
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