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Viral Evolution and Interferon Resistance of Hepatitis C Virus RNA Replication in a Cell Culture Model

Hepatitis C virus (HCV) replicates through an error-prone process that may support the evolution of genetic variants resistant to the host cell antiviral response and interferon (IFN)-based therapy. We evaluated HCV-IFN interactions within a long-term culture system of Huh7 cell lines harboring diff...

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Autors principals: Sumpter, Rhea, Wang, Chunfu, Foy, Eileen, Loo, Yueh-Ming, Gale, Michael
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC523295/
https://ncbi.nlm.nih.gov/pubmed/15479800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.21.11591-11604.2004
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