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Viral Evolution and Interferon Resistance of Hepatitis C Virus RNA Replication in a Cell Culture Model
Hepatitis C virus (HCV) replicates through an error-prone process that may support the evolution of genetic variants resistant to the host cell antiviral response and interferon (IFN)-based therapy. We evaluated HCV-IFN interactions within a long-term culture system of Huh7 cell lines harboring diff...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC523295/ https://ncbi.nlm.nih.gov/pubmed/15479800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.21.11591-11604.2004 |
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