T cell receptor (TCR) clustering in the immunological synapse integrates TCR and costimulatory signaling in selected T cells

During T cell activation, T cell receptors (TCR) cluster at the center of the T cell/antigen-presenting cell interface forming a key component of the immunological synapse. The function of this TCR clustering is still unresolved. A comprehensive search for such a function yielded a very limited and...

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Detalles Bibliográficos
Main Authors: Purtic, Bozidar, Pitcher, Lisa A., van Oers, Nicolai S. C., Wülfing, Christoph
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC549456/
https://ncbi.nlm.nih.gov/pubmed/15703298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406867102
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