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Highly sensitive and multiplexed analysis of CpG methylation at single-base resolution with ligation-based exponential amplification

DNA methylation is a primary epigenetic mechanism for transcriptional regulation during normal development and the occurrence of diseases, including cancers. DNA methylation has been increasingly utilized as a biomarker for cancer detection and differential diagnosis. Generally, one type of cancer i...

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Détails bibliographiques
Publié dans:Chem Sci
Auteurs principaux: Su, Fengxia, Wang, Limei, Sun, Yueying, Liu, Chenghui, Duan, Xinrui, Li, Zhengping
Format: Artigo
Langue:Inglês
Publié: Royal Society of Chemistry 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494546/
https://ncbi.nlm.nih.gov/pubmed/28706642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4sc03135k
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