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Mitochondrial permeability transition involves dissociation of F(1) F(O) ATP synthase dimers and C‐ring conformation

The impact of the mitochondrial permeability transition (MPT) on cellular physiology is well characterized. In contrast, the composition and mode of action of the permeability transition pore complex (PTPC), the supramolecular entity that initiates MPT, remain to be elucidated. Specifically, the pre...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Bonora, Massimo, Morganti, Claudia, Morciano, Giampaolo, Pedriali, Gaia, Lebiedzinska‐Arciszewska, Magdalena, Aquila, Giorgio, Giorgi, Carlotta, Rizzo, Paola, Campo, Gianluca, Ferrari, Roberto, Kroemer, Guido, Wieckowski, Mariusz R, Galluzzi, Lorenzo, Pinton, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494524/
https://ncbi.nlm.nih.gov/pubmed/28566520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643602
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