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The carboxyl-terminal region of cyclic nucleotide-modulated channels is a gating ring, not a permeation path
The recent elucidation of the structure of the carboxyl-terminal region of the hyperpolarization-activated cyclic nucleotide-modulated (HCN2) channel has prompted us to investigate a curious feature of this structure in HCN2 channels and in the related CNGA1 cyclic nucleotide-gated (CNG) channels. T...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2005
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC549449/ https://ncbi.nlm.nih.gov/pubmed/15710893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408323102 |
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