AMPKα1‐LDH pathway regulates muscle stem cell self‐renewal by controlling metabolic homeostasis

Control of stem cell fate to either enter terminal differentiation versus returning to quiescence (self‐renewal) is crucial for tissue repair. Here, we showed that AMP‐activated protein kinase (AMPK), the master metabolic regulator of the cell, controls muscle stem cell (MuSC) self‐renewal. AMPKα1(−...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Theret, Marine, Gsaier, Linda, Schaffer, Bethany, Juban, Gaëtan, Ben Larbi, Sabrina, Weiss‐Gayet, Michèle, Bultot, Laurent, Collodet, Caterina, Foretz, Marc, Desplanches, Dominique, Sanz, Pascual, Zang, Zizhao, Yang, Lin, Vial, Guillaume, Viollet, Benoit, Sakamoto, Kei, Brunet, Anne, Chazaud, Bénédicte, Mounier, Rémi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494470/
https://ncbi.nlm.nih.gov/pubmed/28515121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695273
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