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Glycolytic inhibition by 2-deoxy-d-glucose abolishes both neuronal and network bursts in an in vitro seizure model

Neuronal activity is energy demanding and coupled to cellular metabolism. In this study, we investigated the effects of glycolytic inhibition with 2-deoxy-d-glucose (2-DG) on basal membrane properties, spontaneous neuronal firing, and epileptiform network bursts in hippocampal slices. The effect of...

詳細記述

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書誌詳細
出版年:J Neurophysiol
主要な著者: Shao, Li-Rong, Stafstrom, Carl E.
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494374/
https://ncbi.nlm.nih.gov/pubmed/28404824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00100.2017
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