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Silencing of FABP1 ameliorates hepatic steatosis, inflammation, and oxidative stress in mice with nonalcoholic fatty liver disease

Nonalcoholic fatty liver disease (NAFLD) is increasing in prevalence worldwide and has been identified as a risk factor for cirrhosis and hepatocellular carcinoma. However, there is no effective pharmacologic treatment for NAFLD. FABP1 is a liver‐specific fatty acid‐binding protein (FABP) that plays...

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Bibliographische Detailangaben
Veröffentlicht in:FEBS Open Bio
Hauptverfasser: Mukai, Takako, Egawa, Miki, Takeuchi, Tamaki, Yamashita, Hitoshi, Kusudo, Tatsuya
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494302/
https://ncbi.nlm.nih.gov/pubmed/28680813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12240
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