Enterolactone Suppresses Proliferation, Migration and Metastasis of MDA-MB-231 Breast Cancer Cells Through Inhibition of uPA Induced Plasmin Activation and MMPs-Mediated ECM Remodeling

BACKGROUND: To enhance their own survival, tumor cells can manipulate their microenvironment through remodeling of the extra cellular matrix (ECM). The urokinase-type plasminogen activator (uPA) system catalyzes plasmin production which further mediates activation of matrix metalloproteinases (MMPs)...

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Detalhes bibliográficos
Publicado no:Asian Pac J Cancer Prev
Main Authors: Mali, Aniket V, Joshi, Asavari A, Hegde, Mahabaleshwar V, Kadam, Shivajirao S
Formato: Artigo
Idioma:Inglês
Publicado em: West Asia Organization for Cancer Prevention 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494239/
https://ncbi.nlm.nih.gov/pubmed/28545187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22034/APJCP.2017.18.4.905
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