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Comparison of the effects of olsalazine and decitabine on the expression of CDH1 and uPA genes and cytotoxicity in MDA-MB-231 breast cancer cells

BACKGROUND AND PURPOSE: Since DNA methyltransferase enzymes play a key role in DNA methylation, they can be used as a target to alter epigenetic changes and treat cancer. Recent studies have shown that olsalazine, through its potent inhibitory effect on the DNA methyltransferase enzyme, can be a goo...

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Bibliografiske detaljer
Udgivet i:Res Pharm Sci
Main Authors: Asl, Misagh Mohammadi, Asl, Javad Mohammadi, Naghitorabi, Mojgan
Format: Artigo
Sprog:Inglês
Udgivet: Wolters Kluwer - Medknow 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8216162/
https://ncbi.nlm.nih.gov/pubmed/34221061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1735-5362.314826
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