Anti-Platelet Factor 4/Heparin Antibody Formation Occurs Endogenously and at Unexpected High Frequency in Polycythemia Vera

BACKGROUND: Myeloproliferative neoplasms (MPN) encounter thromboses due to multiple known risk factors. Heparin-induced thrombocytopenia (HIT) is a thrombotic syndrome mediated by anti-platelet factor 4 (PF4)/heparin antibodies with undetermined significance for thrombosis in MPN. We hypothesized th...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Meyer, Sara C., Steinmann, Eva, Lehmann, Thomas, Muesser, Patricia, Passweg, Jakob R., Skoda, Radek C., Tsakiris, Dimitrios A.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494054/
https://ncbi.nlm.nih.gov/pubmed/28698883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/9876819
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