Ex vivo expanded natural killer cells from breast cancer patients and healthy donors are highly cytotoxic against breast cancer cell lines and patient-derived tumours

BACKGROUND: Natural killer (NK) cells play a critical role in cancer immunosurveillance. Recent developments in NK cell ex-vivo expansion makes it possible to generate millions of activated NK cells from a small volume of peripheral blood. We tested the functionality of ex vivo expanded NK cells in...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res
Main Authors: Shenouda, Mira M., Gillgrass, Amy, Nham, Tina, Hogg, Richard, Lee, Amanda J., Chew, Marianne V., Shafaei, Mahsa, Aarts, Craig, Lee, Dean A., Hassell, John, Bane, Anita, Dhesy-Thind, Sukhbinder, Ashkar, Ali A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5493877/
https://ncbi.nlm.nih.gov/pubmed/28668076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-017-0867-9
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