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Overexpression of IL-15 promotes tumor destruction via NK1.1+ cells in a spontaneous breast cancer model
BACKGROUND: Natural Killer (NK) cells play an important role in tumor prevention, but once tumors form, the numbers as well as the cytotoxic functions of NK cells are reduced. IL-15 is a cytokine that increases and activates NK cells. Here we will examine the anti-tumor role of IL-15 in a spontaneou...
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| Publicado no: | BMC Cancer |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4428091/ https://ncbi.nlm.nih.gov/pubmed/25879689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1264-3 |
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