DR5 Knockout Mice Are Compromised in Radiation-Induced Apoptosis

DR5 (also called TRAIL receptor 2 and KILLER) is an apoptosis-inducing membrane receptor for tumor necrosis factor-related apoptosis-inducing ligand (also called TRAIL and Apo2 ligand). DR5 is a transcriptional target of p53, and its overexpression induces cell death in vitro. However, the in vivo b...

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Detalhes bibliográficos
Main Authors: Finnberg, Niklas, Gruber, Joshua J., Fei, Peiwen, Rudolph, Dorothea, Bric, Anka, Kim, Seok-Hyun, Burns, Timothy F., Ajuha, Hope, Page, Robert, Wu, Gen Sheng, Chen, Youhai, McKenna, W. Gillies, Bernhard, Eric, Lowe, Scott, Mak, Tak, El-Deiry, Wafik S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC549384/
https://ncbi.nlm.nih.gov/pubmed/15713653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.5.2000-2013.2005
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