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The relative contribution of pro-apoptotic p53 target genes in the triggering of apoptosis following DNA damage in vitro and in vivo

The p53 pathway displays a large degree of redundancy in the expression of a number of pro-apoptotic mechanisms following DNA damage that, among others, involves increased expression of several pro-apoptotic genes through transactivation. Spatial and temporal cellular contexts contribute to the comp...

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Autores principales: Kuribayashi, Kageaki, Finnberg, Niklas, Jeffers, John R, Zambetti, Gerard P, El-Deiry, Wafik S
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322475/
https://ncbi.nlm.nih.gov/pubmed/21709442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.14.16588
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