SCF(Skp2) Complex Targeted by Epstein-Barr Virus Essential Nuclear Antigen

The stability of cell cycle checkpoint and regulatory proteins is controlled by the ubiquitin-proteasome degradation machinery. A critical regulator of cell cycle molecules is the E3 ubiquitin ligase SCF(Skp2), known to facilitate the polyubiquitination and degradation of p27, E2F, and c-myc. SCF(Sk...

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Detalhes bibliográficos
Main Authors: Knight, Jason S., Sharma, Nikhil, Robertson, Erle S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC549383/
https://ncbi.nlm.nih.gov/pubmed/15713632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.5.1749-1763.2005
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